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Physics in Aging Biology 2024
Emerging Science & Technologies Workshop
Program 2025
August 25
Monday
Munk Cellar
Emerging Tech Schedule
09:10-09:20
Opening
09:10-09:20
Maximilian Unfried
Chair
National University of Singapore
Session 1
Developmental Origins of Regeneration and Aging
09:20-09:40
The axolotl, a new paradigm for probing the links between regeneration and ageing'
Maximina Hee Yun
Chinese Institutes for Medical Research
09:40-10:00
Reconstituting mouse embryogenesis in ex utero systems
Alejandro Aguilera-Castrejon
Howard Hughes Medical Institute Janelia Research Campus
10:00-10:20
Human blastoids, implantation, and implantation failure
Jun Wu
University of Texas Southwestern Medical Center
10:20-10:40
Muse Cells Uncovered: When Science Gets Inspired
Dominik Duscher
MuseCell Innovations
10:40-11:00
Coffee Break
Session 2
Synthetic Control of Life: From Cellular Systems to Lifespan Interventions
11:00-11:20
Building sensor/actuator systems in mammalian cells with synthetic receptors
Elise Cachat
University of Edinburgh
11:20-11:40
Optogenetic engineering of cellular signaling for discovery and therapy
Max Wilson
University of California
11:40-12:00
The third age of humanoid lifespan interventions - synthetic energy to challenge our current barrier
Shahaf Peleg
FBN Dummerstorf
12:00-13:00
Lunch Break
Session 3
Foundation Models for Aging Biology
13:00-13:20
Engineering Longevity Therapeutics with Foundation Models
Jonathan Gootenberg
Harvard Medical School
13:20-13:40
Accessible Frameworks for Biomedical Context and Evaluation of Agents
Sebastian Lobentanzer
Helmholtz Center
13:40-13:50
CpGPT: a Foundation Model for DNA Methylation
Lucas Paulo de Lima Camillo
Stanford University
13:50-14:00
Generative AI for Hybernation and Cryoprotection
Dominika Wilczok
Duke University
14:00-14:30
Coffee Break
Session 4
Virtual Cells: AI at the Helm of Biology
14:30-14:50
Building a Virtual Cell: an AI platform for engineering cell state
Yusuf Roohani
Stanford University
14:50-15:10
Virtual models of biology for programmable regenerative therapeutics
Omar Abudayyeh
Broad Institute of MIT and Harvard
15:10-15:30
Designing genomes using whole-cell models and AI
Lucia Marucci
University of Bristol
15:30-16:00
Coffee Break
16:00-16:45 Session 5 - Panel Discussion
The Path forward for Foundation Models and Virtual Cells
-
Sebastien Thuault
Moderator
Nature Aging
-
Yusuf Roohani
Stanford University
-
Sebastian Lobentanzer
Helmholtz Center
-
Lucia Marucci
University of Bristol
-
Omar Abudayyeh
Broad Institute of MIT and Harvard
16:45-17:10
Coffee Break
Session 6
Engineering Aging: From Structure to Rejuvenation
17:10-17:30
Architectures of immunological aging and regeneration
Sophia Liu
Ragon Institute of MGB, MIT, and Harvard
17:30-17:50
Probing the Wrinkles of the Nucleus in Aging Cells
Wenting Zhao
Nanyang Technological University
17:50-18:10
Engineering Longevity - Computationally-guided reprogramming of single-cell aging.
Nan Hao
University of California San Diego