Opening

Maximilian Unfried

Chair

National University of Singapore

Developmental Origins of Regeneration and Aging

The axolotl, a new paradigm for probing the links between regeneration and ageing'

Maximina Hee Yun

Chinese Institutes for Medical Research

Reconstituting mouse embryogenesis in ex utero systems

Alejandro Aguilera-Castrejon

Howard Hughes Medical Institute Janelia Research Campus

Human blastoids, implantation, and implantation failure

Jun Wu

University of Texas Southwestern Medical Center

Comparison of MSCs and Muse cells: the possible use for healthspan optimization

Dominik Duscher

MuseCell Innovations

Coffee Break

Synthetic Control of Life: From Cellular Systems to Lifespan Interventions

Building sensor/actuator systems in mammalian cells with synthetic receptors

Elise Cachat

University of Edinburgh

Optogenetic engineering of cellular signaling for discovery and therapy

Max Wilson

University of California

The third age of humanoid lifespan interventions - synthetic energy to challenge our current barrier

Shahaf Peleg

FBN Dummerstorf

Lunch Break

Foundation Models for Aging Biology

Engineering Longevity Therapeutics with Foundation Models

Jonathan Gootenberg

Harvard Medical School

Accessible Frameworks for Biomedical Context and Evaluation of Agents

Sebastian Lobentanzer

Helmholtz Center

CpGPT: a Foundation Model for DNA Methylation

Lucas Paulo de Lima Camillo

Stanford University

Generative AI for Hybernation and Cryoprotection

Dominika Wilczok

Duke University

Coffee Break

Virtual Cells: AI at the Helm of Biology

Building a Virtual Cell: an AI platform for engineering cell state

Yusuf Roohani

Stanford University

Virtual models of biology for programmable regenerative therapeutics

Omar Abudayyeh

Broad Institute of MIT and Harvard

Designing genomes using whole-cell models and AI

Lucia Marucci

University of Bristol

Coffee Break

The Path forward for Foundation Models and Virtual Cells

Sebastien Thuault

Moderator

Nature Aging

Yusuf Roohani

Stanford University

Sebastian Lobentanzer

Helmholtz Center

Lucia Marucci

University of Bristol

Omar Abudayyeh

Broad Institute of MIT and Harvard

Coffee Break

Engineering Aging: From Structure to Rejuvenation

Architectures of immunological aging and regeneration

Sophia Liu

Ragon Institute of MGB, MIT, and Harvard

Probing the Wrinkles of the Nucleus in Aging Cells

Wenting Zhao

Nanyang Technological University

Engineering Longevity - Computationally-guided reprogramming of single-cell aging.

Nan Hao

University of California San Diego