ARDD Main Track
Program 2025
August 25
Monday
Main Hall
ARDD2025_MainTrack_Aug25
08:00-09:00
Registrations, coffee, tea
09:00-09:15
Opening remarks
David Dreyer Lassen
Rector of University of Copenhagen
09:15-09:30
Welcoming remark by chairs
Morten Scheibye-Knudsen
University of Copenhagen
Alex Zhavoronkov
Insilico Medicine
Daniela Janina Bakula
University of Copenhagen
Evelyne Yehudit Bischof
Sheba Longevity Center
09:30-20:00
August 26
Tuesday
Main Hall
ARDD2025_MainTrack_Program_Aug26
08:00-09:00
Registrations, coffee, tea
09:00-09:10
Welcome
Morten Scheibye-Knudsen
University of Copenhagen
Alex Zhavoronkov
Insilico Medicine
Daniela Janina Bakula
University of Copenhagen
09:00-18:30
09:10-09:30
Tweaking behavior and processing of Alzheimer’s Ab-Peptides with chemistry
Morten Meldal
University of Copenhagen
09:30-09:50
Reprogramming Aging as a Gateway to Disease Prevention and Healthy Longevity
Jean-Marc Lemaitre
Institute of Regenerative Medicine and Biotherapies of Montpellier
09:50-10:10
Addressing Aging and Disease through Partial Cellular Reprogramming
Juan Carlos Belmonte
Altos Labs
10:10-10:30
Coffee break
10:30-10:50
Epigenetic reprogramming: Local and distant rejuvenating effects
Thomas Rando
University of California Los Angeles
10:50-11:10
11:10-11:30
Brain organoids uncover age-related neuronal vulnerability in Parkinson's disease
Michela Deleidi
Institut Imagine
11:30-13:00
Lunch
13:00-13:20
Intersection of tumorigenesis and aging-associated decline in lung regenerative potential
Tuomas Tammela
Memorial Sloan Kettering Cancer Center
13:20-13:40
13:40-14:00
Targeting inflammaging to enhance health span
Miriam Merad
Mount Sinai School of Medicine in New York
14:00-14:20
Coffee break
14:20-17:20
Edward Rudnic
Session Chair
Maxwell Biosciences
14:20-14:40
Molecular regulation of NAD+ homeostasis in human aging
Riekelt Houtkooper
University of Amsterdam
14:40-15:00
15:00-15:20
Measure and Intervene Aging with AI
Jackie Han
Peking University
15:20-16:00
Coffee break and poster session
16:00-16:20
Imaging of chromatin and epigenetics reveals cell identity and biological age
Alexey Terskikh
Harry Perkins Institute & University of Western Australia, Australia
16:20-16:40
16:40-17:00
Single-Cell and Spatial Multiomics Reveal Novel Cardiomyocyte States in the Human Heart
Christoph Kuppe
Aachen University
17:00-17:20
Frontiers in Epigenetic Clocks: Unlocking Longevity
Steve Horvath
Altos Labs
17:20-17:40
Coffee break
17:40-18:40
Pharma panel: How do we advance longevity in pharma in a credible way?
Clive Cookson
Moderator
Financial Times
Alex Zhavoronkov
Insilico Medicine
Berthil Clasen
Eli Lilly and Company
Priya Singhal
Biogen
Xing Li Wang
Fosun Pharma
18:40
Dinner
19:00
(for speakers only)
August 27
Wednesday
Main Hall
ARDD2025_MainTrack_Aug27
08:00-09:00
Registrations, coffee, tea
09:00-09:10
Welcome
09:10-09:30
Predictions, Tools, and Updates from the Study of Longitudinal Aging in Mice (SLAM)
Rafael de Cabo
National Institute on Aging
09:30-09:50
09:50-10:10
When a calorie is not just a calorie: The regulation of health and longevity by dietary macronutrients
Dudley Lamming
University of Wisconsin-Madison
10:10-10:30
Break
10:30-10:50
Muscling in on mitochondrial aging: Skeletal muscle as a driver and target of bioenergetic decline
Lykke Sylow
University of Copenhagen
10:50-11:10
11:10-11:30
Subliminal hypoxia and accelerated aging
Luigi Ferrucci
National Institute on Aging
11:30-13:00
Lunch and group photo
13:00-14:00
Peter Fedichev
Session Chair
Gero
13:00-13:20
Data Driven Interventions in Human Aging
Morten Scheibye-Knudsen
University of Copenhagen
13:20-13:40
Spatial Mapping of Aged and Senescent Brain Cell Fates
Marissa Schafer
Mayo Clinic
13:40-14:00
Transposons in aging and reproductive aging
Andrei Seluanov
University of Rochester
14:00-14:20
Coffee break
14:20-14:35
Spatial and molecular reorganization of cerebellar microglia with aging
Andy Poyi Tsai
Stanford University
14:35-14:50
Identification of deubiquitinating enzymes (DUBs) regulating seeded tau aggregation in in vitro tauopathy models: new therapeutic strategies for tauopathies?
Christiane Volbracht
Lundbeck
14:50-15:05
Targeting CD38 immunometabolic checkpoint to supercharge T cell immunity in Alzheimer's disease.
Javier María Peralta Ramos
Weizmann Institute of Science
15:05-15:20
Universal Transcriptomic Hallmarks of Mammalian Aging and Mortality across Species and Cell Types
Alexander Tyshkovskiy
Harvard Medical School
15:20-16:00
Coffee break and poster session
16:00-16:20
The 5“A”: ageing, autophagy, Alzheimer’s, Artificial intelligence, and an “A molecule” in healthy longevity
Evandro Fang
University of Oslo
16:20-16:40
Epigenetic Reprogramming of Cell Fates: Mechanisms and Applications
Ethan Liu
Westlake University
16:40-17:00
Targeting selective autophagy: ensuring healthy longevity one protein at a time
Ana Maria Cuervo
Albert Einstein College of Medicine
17:00-17:20
Coffee break
17:20-17:40
17:40-18:00
18:00-18:20
18:20-19:00
Dinner
19:00-19:20
Lessons from COVID-19: Reducing Global Vulnerability in the Age of Longevity
Michael Levitt
Stanford University
19:20-19:40
19:40-20:00
20:00-20:15
Break
20:15-20:55
Investor Panel-Early Stage
Tom Zuber
Moderator
Zuber Lawler
Garri Zmudze
LongeVC
William Harborne
LongGame
Anne Marije van Harten
Apollo Health Ventures
21:00-21:40
Investor Panel-Growth Stage
Tom Zuber
Moderator
Zuber Lawler
Murali Venkatesan
Danaher Corporation
Kitsu Egerton
Baillie Gifford
Daisy Cai
B Capital
August 28
Thursday
Main Hall
ARDD2025_MainTrack_Aug28
08:00-12:00
Registrations, coffee, tea
09:00-09:10
Welcome
09:00-18:30
Munk Cellar
09:10-09:30
Circulatory biomarkers of brain aging
Tony Wyss-Coray
Stanford University
09:30-09:50
09:50-10:10
Brain Aging and Blood Factors
Lida Katsimpardi
Institute for Regenerative Medicine and Biotherapies
10:10-10:30
Break
10:30-10:50
Quantifying and Targeting Aging
Vadim Gladyshev
Harvard Medical School
10:50-11:10
hTSC-Derived Exosomes: Targeting Senescence and Age-Related Diseases
11:10-11:30
Purinergic signaling as a vulnerable node of detrimental senescence
Marco Demaria
European Research Institute for the Biology of Ageing
11:30-13:00
Lunch
13:00-15:15
13:00-13:20
Validating and Implementing Longevity interventions
Brian Kennedy
National University of Singapore
13:20-13:40
13:40-14:00
Biomarkers of Senescence: From Research to Clinical Practice
Nathan Le Brasseur
Mayo Clinic
14:00-14:20
Coffee break
14:20-14:35
Heritability of human lifespan is about ~50% when confounding factors are addressed
Ben Shenhar
Weizmann Institute of Science
14:35-14:50
DREAM complex activity as a determinant of somatic mutation rate and lifespan
Zane Koch
University of California San Diego
14:50-15:05
GDF3 promotes adipose tissue macrophage-mediated inflammation via altered chromatin accessibility during aging
In Hwa Jang
University of Minnesota
15:05-15:20
Use of potential gerotherapeutic drugs and mortality in geriatric rehabilitation inpatients: RESORT
Weilan Wang
National University of Singapore
15:20-16:00
Coffee break and poster session
15:30-18:20
16:00-16:20
Drug discovery for developing regenerative pharmacological interventions targeting diseases of aging
Collin Ewald
Novartis Biomedical Research Diseases of Aging and Regenerative Medicine
16:20-16:40
16:40-17:00
Redrawing the Health Care Map: From Pushing at Boundaries to Redefining Them
Andrew Adams
Eli Lilly and Company
17:00-17:20
Coffee break
17:20-18:20
Luc Aguilar
Session Chair
L'Oréal Research & Innovation
17:20-17:40
Development of novel geroprotectors to extend healthspan
Laura Niedernhofer
University of Minnesota Medical School
17:40-18:00
18:00-18:20
Telomere Biology in aging and age-related diseases: mechanisms and therapies
Fabrizio d'Adda di Fagagna
IFOM; IGM-CNR
18:20-19:00
Dinner
19:00-19:20
Optimal diets for healthy aging
Marta Guasch-Ferré
University of Copenhagen
19:20-19:40
Metabolic drivers of aging
Peter Mullen
University of Southern California
19:40-20:00
Accelerating translational geroscience: new training programs, centers, and clinical applications
John Newman
Buck Institute
20:00-20:20
Break
20:20-21:00
Pharma panel
Lisa Melton
Moderator
Nature Biotechnology
Avi Spier
Novartis
Heinrich Jasper
Genentech Inc.
Kristen Fortney
BioAge Labs
Aisyah Sjöholm
Insilico Medicine
Lars Hartenstein
McKinsey Health Institute
August 29
Friday
Main Hall
ARDD2025_MainTrack_Aug29
08:00-09:00
Registrations, coffee, tea
09:00-09:15
Welcome and Poster + Travel Grant Award ceremony
09:10-09:30
Organ Protection with GLP-1 Receptor Agonists
Lotte Bjerre Knudsen
Novo Nordisk
09:30-09:50
09:50-10:10
A new, translational paradigm for pre-clinical drug testing
Steve Austad
University of Alabama Birmingham
10:10-10:30
Coffee break
10:30-10:50
Lying Still, Falling Fast: How Hospital Beds Accelerate Aging
Charlotte Suetta
University of Copenhagen
10:50-11:10
11:10-11:30
The anti-inflammatory role of exercise
Bente Klarlund
University of Copenhagen
11:30-13:00
Lunch and Startup Award ceremony
13:00-13:20
Endogenous amyloid beta promotes spontaneous brain aging and learning loss in turquoise killifish
Dario Riccardo Valenzano
Leibniz Institute on Aging
13:20-13:40
13:40-14:00
Telomeres, Transcriptomes and Troubles: Bats as new models of extended healthspan
Emma Teeling
University College Dublin
14:00-14:20
Coffee break
14:20-14:35
Restoration of biological age during prolonged fasting-refeeding modulated by a nutrient-regulated linker histone
Kazuto Kawamura
Max Planck Institute for Biology of Ageing
14:35-14:50
Rapid Skin Senescence Switch: A Druggable Checkpoint for Anti‑Senescence Therapies
Tomaz Rozmaric
Ludwig Boltzmann Institute for Traumatology in Vienna
14:50-15:05
Aging of Elastin: From Structural Decay to Therapeutic Potential
Andrea Heinz
University of Copenhagen
15:05-15:20
A novel disease-modifying osteoarthritis drug affect cartilage degeneration and pain, discovered through in vivo screening
Martin Borch Jensen
Gordian Biotechnology
15:20-16:00
Coffee break
16:00-16:20
The Aging Genome: From Mechanisms to Interventions
Björn Schumacher
University of Cologne
16:20-16:40
16:40-17:00
DNA damage and Aging: the impact of nutrition, gene size and transcription on neurodegeneration
Jan Hoeijmakers
University of Cologne
17:00-17:20
Coffee break
17:20-17:40
Genomic Insights into Reproductive Ageing
Anna Murray
University of Exeter
17:40-18:00
18:00-18:20
Mechanisms of Ovarian Aging: A Target for Geroprotection in Women
Yousin Suh
Columbia University
18:20-19:00
Dinner
19:00-19:20
19:20-19:40
Targeting CD38 against aging
Eric Verdin
Buck Institute for Research on Aging
19:40-20:00
Quantitative and dynamic analysis of organismal aging
Anne Brunet
Stanford University
20:00-20:10
Wrap up