Predictions, Tools, and Updates from the Study of Longitudinal Aging in Mice (SLAM)
Rafael de Cabo
National Institute on Aging
09:30-09:50
Repair Biotechnologies
Sponsor talk - with gratitude
Breaking the Cholesterol Curse: How Purging Hidden Cellular Buildup Can Reverse Cardiovascular Disease.
Mourad Topors
09:50-10:10
When a calorie is not just a calorie: The regulation of health and longevity by dietary macronutrients
Dudley Lamming
University of Wisconsin-Madison
10:10-10:30
Break
10:30-10:50
Muscling in on mitochondrial aging: Skeletal muscle as a driver and target of bioenergetic decline
Lykke Sylow
University of Copenhagen
10:50-11:10
Rejuvenate Biomed
Sponsor talk - with gratitude
Clinical development of RJx-01 as a novel combination drug for the treatment of sarcopenia
Jeroen Aerssens
11:10-11:30
Subliminal hypoxia and accelerated aging
Luigi Ferrucci
National Institute on Aging
11:30-13:00
Lunch and group photo
13:00-14:00
Peter Fedichev
Session Chair
Gero
13:00-13:20
Data Driven Interventions in Human Aging
Morten Scheibye-Knudsen
University of Copenhagen
13:20-13:40
Spatial Mapping of Aged and Senescent Brain Cell Fates
Marissa Schafer
Mayo Clinic
13:40-14:00
Transposons in aging and reproductive aging
Andrei Seluanov
University of Rochester
14:00-14:20
Coffee break
14:20-14:35
Spatial and molecular reorganization of cerebellar microglia with aging
Andy Poyi Tsai
Stanford University
14:35-14:50
Identification of deubiquitinating enzymes (DUBs) regulating seeded tau aggregation in in vitro tauopathy models: new therapeutic strategies for tauopathies?
Christiane Volbracht
Lundbeck
14:50-15:05
Targeting CD38 immunometabolic checkpoint to supercharge T cell immunity in Alzheimer's disease.
Javier María Peralta Ramos
Weizmann Institute of Science
15:05-15:20
Universal Transcriptomic Hallmarks of Mammalian Aging and Mortality across Species and Cell Types
Alexander Tyshkovskiy
Harvard Medical School
15:20-16:00
Coffee break and poster session
16:00-16:20
The 5“A”: ageing, autophagy, Alzheimer’s, Artificial intelligence, and an “A molecule” in healthy longevity
Evandro Fang
University of Oslo
16:20-16:40
Epigenetic Reprogramming of Cell Fates: Mechanisms and Applications
Ethan Liu
Westlake University
16:40-17:00
Targeting selective autophagy: ensuring healthy longevity one protein at a time
Ana Maria Cuervo
Albert Einstein College of Medicine
17:00-17:20
Coffee break
17:20-17:40
The Thalion Initiative
Sponsor talk - with gratitude
Closing the Gaps in Aging Biology via a Coordinated Approach
Todd White
17:40-18:00
Infinita City
Sponsor talk - with gratitude
Frontier Jurisdictions & Changing the Regulatory Paradigm for Longevity
Niklas Anzinger
18:00-18:20
Aptah Bio
Sponsor talk - with gratitude
U1 snRNP: A Key Molecular Switch in Age-Related Diseases
Vanessa Sinatti
18:20-19:00
Dinner
19:00-19:20
Lessons from COVID-19: Reducing Global Vulnerability in the Age of Longevity
Michael Levitt
Stanford University
19:20-19:40
Insilico Medicine
Sponsor talk - with gratitude
From Disease to Discovery: Leveraging IPF Aging Biology for Novel Therapeutic Targets
Fedor Galkin
19:40-20:00
LongeVC
Sponsor talk - with gratitude
4 years into longevity investing: Takeaways deploying an early stage fund
Novel NLRP3 inflammasome inhibitors: From structural discovery to clinical trial
Rusty Montgomery
09:50-10:10
A new, translational paradigm for pre-clinical drug testing
Steve Austad
University of Alabama Birmingham
10:10-10:30
Coffee break
10:30-10:50
Lying Still, Falling Fast: How Hospital Beds Accelerate Aging
Charlotte Suetta
University of Copenhagen
10:50-11:10
XPRIZE Healthspan
Sponsor talk - with gratitude
Global Innovations Landscape in XPRIZE Healthspan
Jamie Justice
11:10-11:30
The anti-inflammatory role of exercise
Bente Klarlund
University of Copenhagen
11:30-13:00
Lunch and Startup Award ceremony
13:00-13:20
Endogenous amyloid beta promotes spontaneous brain aging and learning loss in turquoise killifish
Dario Riccardo Valenzano
Leibniz Institute on Aging
13:20-13:40
Deep Origin
Sponsor talk - with gratitude
Towards Integrated Multi-Level Physics and ML for Aging and Drug Discovery
Michael Antonov
13:40-14:00
Telomeres, Transcriptomes and Troubles: Bats as new models of extended healthspan
Emma Teeling
University College Dublin
14:00-14:20
Coffee break
14:20-14:35
Restoration of biological age during prolonged fasting-refeeding modulated by a nutrient-regulated linker histone
Kazuto Kawamura
Max Planck Institute for Biology of Ageing
14:35-14:50
Rapid Skin Senescence Switch: A Druggable Checkpoint for Anti‑Senescence Therapies
Tomaz Rozmaric
Ludwig Boltzmann Institute for Traumatology in Vienna
14:50-15:05
Aging of Elastin: From Structural Decay to Therapeutic Potential
Andrea Heinz
University of Copenhagen
15:05-15:20
A novel disease-modifying osteoarthritis drug affect cartilage degeneration and pain, discovered through in vivo screening
Martin Borch Jensen
Gordian Biotechnology
15:20-16:00
Coffee break
16:00-16:20
The Aging Genome: From Mechanisms to Interventions
Björn Schumacher
University of Cologne
16:20-16:40
Rejuve.Bio
Sponsor talk - with gratitude
Building an AI Research Collective for Longevity Discovery
Kennedy Schaal
16:40-17:00
DNA damage and Aging: the impact of nutrition, gene size and transcription on neurodegeneration
Jan Hoeijmakers
University of Cologne
17:00-17:20
Coffee break
17:20-17:40
Genomic Insights into Reproductive Ageing
Anna Murray
University of Exeter
17:40-18:00
Gero
Sponsor talk - with gratitude
Cooling the Clock: Effective Temperature, Noise, and Closing the 40-Year Longevity Gap
Peter Fedichev
18:00-18:20
Mechanisms of Ovarian Aging: A Target for Geroprotection in Women
Yousin Suh
Columbia University
18:20-19:00
Dinner
19:00-19:20
Insilico Medicine
Sponsor talk - with gratitude
Discovery and Development of Longevity Therapeutics: When Should We See the First Rationally-designed Geroprotectors with the Clinical Longevity Protocol?
Alex Zhavoronkov
19:20-19:40
Targeting CD38 against aging
Eric Verdin
Buck Institute for Research on Aging
19:40-20:00
Quantitative and dynamic analysis of organismal aging