Ceremonial Hall
Ceremonial Hall and Munk Cellar
Munk Cellar
Munk Cellar
August 26-30
August 26-28
August 26
August 27
Main Track
Monday, August 26
08:00 - 09:00 (CET)
Registrations, coffee, tea
09:00 - 09:30 (CET)
Opening remarks
Henrik Wegener, Rector of the University of Copenhagen, Denmark
Mette Kierkgaard, Minister for Senior Citizens, Denmark
09:30 - 20:00 (CET)
Parallel sessions:
Longevity Medicine Track
XPRIZE Healthspan Team Summit
Click here for program
Emerging Science &
Technologies Workshop
Click here for program
Longevity Medicine Track
XPRIZE Healthspan Team Summit
Click here for program
Emerging Science &
Technologies Workshop
Click here for program
19:00 (CET)
Dinner
08:00 - 09:00 (CET)
Registrations, coffee, tea
9:00 - 9:10 (CET)
ARDD Chairs
Morten Scheibye-Knudsen, University of Copenhagen, Denmark
Daniela Bakula, University of Copenhagen, Denmark
Alex Zhavoronkov, Insilico Medicine, USA
09:10 - 09:30 (CET)
Can we ameliorate the metabolic complications of aging with the GLP-1 receptor agonists?
Jens Juul Holst, University of Copenhagen, Denmark
09:30 - 09:50 (CET)
The Novo Nordisk Foundation – from basic biomedical discoveries to clinical translation, through strategic partnering
Marie Kveiborg, Novo Nordisk Foundation, Denmark
09:50 - 10:10 (CET)
Preserving muscle mass for healthy aging: Old tricks and new targets
Lykke Sylow, University of Copenhagen, Denmark
10:10 - 10:30 (CET)
Coffee break
10:30 - 10:50 (CET)
Improved resilience and proteostasis mediate longevity upon DAF-2 degradation in old age
Collin Ewald, Novartis, Switzerland
10:50 - 11:10 (CET)
Value Inflection Points: Successful Balancing of Expectations & Reality
Georg Nebgen, LongeVC, Switzerland
11:10 - 11:30 (CET)
RNA Medicines to Increase Healthspan: Therapeutic Targeting of Pathological RNAs in Aging-Related Diseases.
Anders M. Näär, University of California, Berkeley, USA
11:30 - 13:00 (CET)
Lunch and Break-out lunch:
12:00 - 12:30 (CET)
Break-out Lunch session presented by Inspire Longevity
Dominika Wilczok, Duke University, USA
Andrea Olsen, California Institute of Technology, USA
Christopher Ren, Shanghai High School International Division, Shanghai
Session sponsored by Maxwell Biosciences
J. “Scotch” McClure, Maxwell Biosciences, USA
Moderator
Moderator
13:00 - 13:20 (CET)
Targeting immune function in older organisms
Christina Camell, Institute on the Biology of Aging and Metabolism, USA
13:20 - 13:40 (CET)
Polypharmacology targeting gut microbes for health and longevity effects
Filipe Cabreiro, Imperial College London, UK
13:40 - 14:00 (CET)
Is Aging Contagious? Reviewing the known pathogenic drivers of degenerative aging
J. "Scotch" McClure, Maxwell Biosciences, USA
14:00 - 14:20 (CET)
Coffee break
Session sponsored by BioVie
Chris Reading, BioVie, USA
Moderator
Moderator
Daniela Bakula, University of Copenhagen, Denmark
Moderator
Moderator
14:20 - 14:40 (CET)
Transport at the blood-brain barrier
Martin Lauritzen, University of Copenhagen, Denmark
14:40 - 15:00 (CET)
Bezisterim Effects on Biological Age, Alzheimer’s Epigenetics, and Neurologic Assessments
Chris Reading, BioVie, USA
15:00 - 15:20 (CET)
The night life of the brain
Maiken Nedergaard, University of Copenhagen, Denmark
15:20 - 16:00 (CET)
Poster Session
16:00 - 16:20 (CET)
Engineering Healthy Aging in Females
Jennifer Garrison, Buck Institute, USA
16:20 - 16:40 (CET)
What can be done about the aging brain? - New advances in pharmatherapy
Johan Luthman , Lundbeck, Denmark
16:40 - 17:00 (CET)
Blood-based approaches to counter brain aging
Saul Villeda, University of California, USA
17:00 - 17:20 (CET)
Coffee break
17:20 - 17:40 (CET)
Living Longer and Healthier by Training Innate Immunity: Transforming Aging
Hal Gunn, Qu Biologics, Canada
17:40 - 18:00 (CET)
Long-Term Improvements in Key Biomarkers in a Real-World Cohort of Digital Health Platform Users
Gil Blander, InsideTracker, USA
18:00 - 18:20 (CET)
Methylation Clocks and AI Life Models as Sources of Therapeutic Targets
Alex Zhavoronkov, Insilico Medicine, USA
18:20 - 19:00 (CET)
Dinner
19:00 - 19:20 (CET)
In vitro heterochronic parabiosis identifies a multi-tissue geroprotective factor from young blood
Yousin Suh, Columbia University, USA
19:20 - 19:40 (CET)
Cellular senescence solutions: pioneering advances in clinical practice
Natalia Mitin, Sapere Bio, USA
19:40 - 20:00 (CET)
Treatment of neurodegenerative disorders with reverse transcriptase inhibitors
John Sedivy, Brown University, USA
20:00 - 20:20 (CET)
Translating Geroscience to Clinic
Raghav Sehgal, Healthy Longevity clinic, USA
20:20 - 21:00 (CET)
Investor Panel: How do we build a longevity biotechnology industry?
Lisa Melton, Nature Biotechnology
Moderator
Moderator
Garri Zmudze, LongeVC, Switzerland
Lars Hartenstein, McKinsey Health Institute, USA
Michael Baran, Pfizer, Inc., USA
Petr Sramek, Healthy Longevity Clinic, USA
Marie Kveiborg, Novo Nordisk Foundation, Denmark
Alex Zhavoronkov, Insilico Medicine, USA
08:00 - 09:00 (CET)
Registrations, coffee, tea
09:00 - 09:10 (CET)
Welcome!
Session sponsored by L’ORÉAL R&I
Anne Colonna, L’ORÉAL R&I, France
Moderator
Moderator
09:10 - 09:30 (CET)
Genome Stability in Aging: Mechanisms and Targets
Björn Schumacher, University of Cologne, Germany
09:30 - 09:50 (CET)
R-loop instability drives premature aging in Woodhouse-Sakati syndrome
Daniela Bakula, University of Copenhagen, Denmark
09:50 - 10:10 (CET)
Functional impact of somatic mutations in aging: role of negative selection
Jan Vijg, Albert Einstein College of Medicine, USA
10:10 - 10:30 (CET)
Break
10:30 - 10:50 (CET)
Can genetic medicine give us a world without disease
Andrew Adams, Eli Lilly & Company, USA
10:50 - 11:10 (CET)
Drug target discovery for metabolic disease at the intersection of exercise and aging
Naisha Shah, BioAge, USA
11:10 - 11:30 (CET)
Insights into stem cell longevity, rejuvenation and senescence from diapause
Adam Antebi, Max Planck Institute, Germany
11:30 - 13:00 (CET)
Lunch with group photo
12:00 (CET)
Group photo
13:00 - 13:20 (CET)
Novel Strategies for Financing an Early-Stage Biotech Company
Anthony Schwartz, VitaDao, USA
13:20 - 13:40 (CET)
Developing a next-generation buccal clock that associates with lifestyle and mortality
Max Shokhirev, Tally Health, USA
13:40 - 14:00 (CET)
Aging-related gene signatures increasing the risk of age-related disorders
David Glass, Regeneron Pharmaceuticals, Inc., USA
14:00 - 14:20 (CET)
Coffee break
Macsue Jacques, Monash University, Australia
Moderator
Moderator
14:20 - 14:35 (CET)
Tension and Gravity: The Forces at Play in Aging
Zoe Du, Buck institute, USA
14:35 - 14:50 (CET)
Sequencing oxidized guanines, abasic sites, and DNA breaks in the human genome: towards mechanistic biomarkers of aging
Vakil Takhaveev, ETH Zurich, Switzerland
14:50 - 15:05 (CET)
FOXO-regulated OSER1 reduces oxidative stress and extends lifespan in multiple species
Zhiquan Li, University of Copenhagen, Denmark
15:05 - 15:20 (CET)
Recent developments from human studies on the geroprotective potential of metformin
Matthew Thomas Keys, University of Southern Denmark
15:20 - 16:00 (CET)
Poster session
16:00 - 16:20 (CET)
Drug repurposing for Alzheimer's disease using triangulation of evidence
Sara Hägg, Karolinska Institutet, Sweden
16:20 - 16:40 (CET)
Alzheimer's Disease and Aging: The time is now
Fraser Hall, Biogen, USA
16:40 - 17:00 (CET)
Measuring Aging with AI
Jing-Dong Jackie Han, Peking-Tsinghua Center for Life Sciences, China
17:00 - 17:20 (CET)
Coffee break
Session sponsored by Life Biosciences
Jerry McLaughlin, Life Biosciences, USA
Moderator
Moderator
17:20 - 17:40 (CET)
Immunometabolic Checkpoints of Inflammaging
Vishwa Deep Dixit, Yale School of Medicine, USA
17:40 - 18:00 (CET)
Partial Epigenetic Reprogramming: A Novel Gene Therapy That Restores Visual Function and Increases RGC Axon Density in a Nonhuman Primate Model of NAION
Jerry McLaughlin, Life Biosciences, USA
18:00 - 18:20 (CET)
Using Network Analysis of Life Course Trajectories in the Study of Longitudinal Aging in Mice (SLAM) to Understand Aging
Rafael de Cabo, National Institutes of Health, USA
18:20 - 19:00 (CET)
Dinner
19:00 (CET)
Gala Dinner (for speakers only) sponsored by:
LongeVC
Longevity Science Foundation
Thursday, August 29
08:00 - 09:00 (CET)
Registrations, coffee, tea
09:00 − 09:10 (CET)
Welcome!
Session sponsored by 199 Biotechnologies
Boris Djordjevic, 199 Biotechnologies, UK
Moderator
Moderator
09:10 - 09:30 (CET)
Geroprotection from combination drug treatments
Linda Partridge, University College London, UK
09:30 - 09:50 (CET)
Translating to clinics
Boris Djordjevic, 199 Biotechnologies, UK
09:50 - 10:10 (CET)
Where are we in the Longevity Quest
Brian Kennedy, National University of Singapore, Singapore
10:10 - 10:30 (CET)
Coffee break
10:30 - 10:50 (CET)
Delayed Aging by Caloric Restriction
Rozalyn Anderson, University of Wisconsin Madison, USA
10:50 - 11:10 (CET)
Beyond Epigenetic Clocks: Methylation Risk Scores and Biomarker Proxies in Agin
Ryan Smith, TruDiagnostic, Inc., USA
11:10 - 11:30 (CET)
Systematic mapping of organism-scale gene-regulatory networks in aging using population asynchrony
Nicholas Edward Stroustrup, Center for Genomic Regulation, Spain
11:30 - 13:00 (CET)
Lunch
12:00 - 13:00 (CET)
Startup Pitch,
Main Hall
Main Hall
Jitka Kolarova, Lead for Innovations in Health and Healthcare
at World Economic Forum
Moderator
at World Economic Forum
Moderator
Sergey Jakimov, LongeVC, Switzerland
Judge
Judge
Katerina Stroponiati, Brilliant Minds,USA
Judge
Judge
Jens Nielsen, BioInnovation Institute, Denmark
Judge
Judge
Presenting starups:
Mmimetika
PURRAI
Vanaheim
Sydra
Ani Biome
Tracked Biotechnologies
ReVamp Bio
Rejuve.bio
Aptah Biociences
Mmimetika
PURRAI
Vanaheim
Sydra
Ani Biome
Tracked Biotechnologies
ReVamp Bio
Rejuve.bio
Aptah Biociences
13:00 - 13:20 (CET)
Reciprocal Paths to Healthy Longevity for All : Integrating AI, Metaverse, and Interdisciplinary Clinical Practice for Both the Healthy and the Sick
Evelyne Bischof, Renji Hospital, Shanghai and Sheba Longevity Center
13:20 - 13:40 (CET)
Microbiome modulation as AI algorithm
Nika Pintar, Ani Biome, Croatia
13:40 - 14:00 (CET)
The Longevity Biotechnology Association: Helping Longevity Biotech thrive and prosper
Risa Starr, Longevity Biotechnology Association, USA
14:00 - 14:20 (CET)
Coffee break
14:20 − 14:35 (CET)
Heterochronic transplantation as a platform to study inter-tissue biological age dynamics
Jesse Poganik, Harvard Medical School, USA
14:35 − 14:50 (CET)
Harnessing epigenetics to estimate Intrinsic Capacity
Matias Fuentealba Valenzuela, University College London (UCL), UK
14:50 − 15:05 (CET)
Axolotl epigenetic clock offers insights into the nature of negligible senescence
Yuliia Haluza, Center for Regenerative Therapies Dresden, Germany
15:05 − 15:20 (CET)
Ribosome machinery is a convergent target in the evolution of mammalian longevity
Domenico DiFraia, Vera Gorbunova's laboratory in Rochester, USA
15:20 - 16.00 (CET)
Poster session
16:00 - 16:20 (CET)
The Science of Longevity : a new path to extend skin healthspan
Luc Aguilar, L’ORÉAL R&I, France
16:20 - 16:40 (CET)
Trophoblast Stem Cell Secretome for Cell Senescence
Kotb Abdelmohsen, National Institute on Aging,
National Institutes of Health, USA
Trophoblast Stem Cell Secretome for Cell Senescence
Yuta Lee, Accelerated Biosciences, USA
16:40 - 17:00 (CET)
NAD and glutathione dynamics in human aging, disease and after NAD-booster treatment
Anu Suomalainen, University of Helsinki, Finland
17:00 - 17:20 (CET)
Coffee break
17:20 - 17:40 (CET)
Age-associated loss of gene expression control
Andreas Beyer, University of Cologne, Germany
17:40 - 18:00 (CET)
Clearance of Excess Intracellular Free Cholesterol Reverses Cardiovascular and Metabolic Disease
Mourad Topors, Repair Biotechnologies, USA
18:00 - 18:20 (CET)
Restoring Immune Function to Ablate Senescent Cells and Treat Diseases of Aging
Robin Mansukhani, Deciduous Therapeutics, USA
18:20 - 19:00 (CET)
Dinner
19:00-19:20 (CET)
Diseases of Aging and Regenerative medicine (DARe) in Novartis: elucidating how age-associated changes intersect with disease to support therapeutic discovery
Mara Fornaro, Novartis, Switzerland
19:20 - 19:40 (CET)
Vittorio Sebastiano, Turn Biotechnologies, USA
19:40 - 20:00 (CET)
The Information Theory of Aging: where do we stand?
David A. Sinclair, Harvard Medical School, USA
20:00 - 20:10 (CET)
Break
20:10 - 21:00 (CET)
Pharma Panel: Preclinical Development: Sourcing Early Stage Innovation in Aging Research for Drug Discovery
Michael Ringel, BCG, USA
Moderator
Moderator
Peng Leong, BioAge Labs, USA
David Glass, Regeneron Pharmaceuticals, Inc., USA
Johan Luthman, Lundbeck, Denmark
Alex Zhavoronkov, Insilico Medicine, USA
Jonathan Matthew Wilson, Eli Lilly and Company, USA
Friday, August 30
08:00 - 09:00 (CET)
Registrations, coffee, tea
09:00 − 09:10 (CET)
Welcome and Poster Award ceremony
09:10 - 09:30 (CET)
Effects of cyclic period feeding restriction in non-human primates
Isabel Beerman, National Institute on Aging, USA
09:30 - 09:50 (CET)
Microgravity Induced Artificial Organ Aging to Identify Geroprotective Drugs
David Furman, Stanford School of Medicine, USA
09:50 - 10:10 (CET)
Improving regeneration of aged muscles
Pura Muñoz-Canoves, Altos Labs, USA
10:10 - 10:30 (CET)
Coffee break
10:30 - 10:50 (CET)
Natural getoprotectors
Alexey Moskalev, George Mason University, USA
10:50 - 11:10 (CET)
NaNots: A Novel Platform for Adsorbing Soluble Drivers of Diseases & Aging
Lou Hawthorne, NaNotics, USA
11:10 - 11:30 (CET)
Taking rejuvenation to longevity escape velocity: combinatorial rejuvenation in mice
Aubrey de Grey, LEV Foundation, USA
11:30 - 13:00 (CET)
Lunch and Startup Award ceremony
Session sponsored by Timeline®
Chris Rinsch, Timeline
Moderator
Moderator
13:00 - 13:20 (CET)
Defining and measuring human immune aging
Eric Verdin, Buck Institute, USA
13:20 - 13:40 (CET)
Mitochondrial remodeling by Urolithin A rejuvenates the human immune system – results from a randomized controlled trial
Dominic Denk, University Hospital Frankfurt,Germany
13:40 - 14:00 (CET)
The Impact of the Postbiotic Urolithin A (Mitopure) on Health and Longevity
Chris Rinsch, Timeline
14:00 - 14:20 (CET)
Coffee break
14:20 − 14:35 (CET)
Inhibition of IL11 signalling extends mammalian healthspan and lifespan
Anissa Anindya Widjaja, Duke-NUS Medical School, Singapore
14:35 − 14:50 (CET)
Senescent cells upregulate PD-L1 to evade immunosurveillance and promote inflammaging
Julia-Magdalena Majewska, Weizmann Institute of Science, Israel
14:50 − 15:05 (CET)
Early-onset partial reprogramming slows down certain age-associated changes in the hematological, immune, and cognitive compartments of NOLIFE non-progeric mice
Luka Culig, National Institute on Aging (NIA), USA
15:05 − 15:20 (CET)
Lipid Aging Clocks as predictive and prognostic biomarker in cancer and inflammaging
Maximilian Unfried, National University of Singapore, VitaDAO
15:20 - 16.00 (CET)
Coffee break
16:00 - 16:20 (CET)
Dual-Purpose Target Discovery and Aging Research with PreciousGPT Models
Frank Pun, Insilico Medicine, Hong Kong
Fedor Galkin, Insilico Medicine AI, Abu Dhabi
16:20 - 16:40 (CET)
PENTADECANOIC ACID (C15:0) AS A GEROPROTECTOR
Evolution, Aging Hallmarks, and a Preponderance of Evidence
Evolution, Aging Hallmarks, and a Preponderance of Evidence
Nicholas Schork, Translational Genomics Research Institute, USA
16:40 - 17:00 (CET)
Epigenetics of aging and longevity
Vera Gorbunova, University of Rochester, USA
17:00 - 17:20 (CET)
Coffee break
17:20 - 17:40 (CET)
Long noncoding RNA LANCL1-AS1 promotes myogenesis and mitochondrial function, declines in old skeletal muscle
Myriam Gorospe, National Institutes of Health (NIH), USA
17:40 - 18:00 (CET)
Circadian Clock Regulation of Aging and Longevity
Joseph Takahashi, University of Texas Southwestern Medical Center, USA
18:00 - 18:20 (CET)
Morten Scheibye-Knudsen, University of Copenhagen, Denmark
18:20 - 19:00 (CET)
Dinner
19:00 - 19:20 (CET)
Organ aging and rejuvenation
Vadim Gladyshev, Harvard Medical School, USA
19:20 - 19:40 (CET)
Developing effective treatments for diseases of aging through pathway-driven drug development
Jeroen Aerssens, Chief Development Officer, Rejuvenate Biomed
19:40 - 20:00 (CET)
DNA methylation studies of maximum lifespan in mammals
Steve Horvath, Altos Labs, USA